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Postdoctoral Appointee - Microbiology/Gene-editing

Sandia National Laboratories


Location:
Livermore, CA
Date:
06/27/2017
2017-06-272017-07-26
Job Code:
657419
Categories:
  • Mechanical Engineering - Applied Mechanics
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Job Details


Job ID: 657419
Company: Sandia National Laboratories
Location: Livermore, CA
Job Title:Postdoctoral Appointee - Microbiology/Gene-editing

:

The Post-Doctoral Appointee Program is designed to recruit outstanding Ph.D. applicants to assist a line organization in meeting its mission objectives and to provide a professional technical work environment for the employee. The Ph.D. must have been conferred within one to five years prior to employment. These assignments are for a one-year period, with the option at management?s discretion to serve no more than five additional one-year assignments.

Sandia/California's Biotechnology and Bioengineering Department is seeking a postdoctoral appointee to join a multidisciplinary team using recent advances in gene editing technology (CRISPR), Next Generation Sequencing (NGS), and materials science for development and characterization of novel in vivo CRISPR delivery platforms. The postdoctoral fellow will identify and optimize host-directed CRISPR constructs that enhance defense against biodefense-related bacterial pathogens in vitro; work with an engineering team to develop nanoparticle-based CRISPR delivery vehicles; and test nanoparticle delivery of the CRISPR constructs in mouse models of bacterial infection. The postdoctoral fellow will also be responsible for the effective communication of research results through publications and conference presentations.

Required:



Candidates must have a recent PhD degree in microbiology, molecular biology, cell biology, immunology, materials science, or a related field. The successful candidate must be a strong individual contributor within a multidisciplinary team comprising biologists, chemists, engineers, and programmers, within the framework of a milestone-driven research project. Strong written and oral communication skills are required. A record of high technical achievement (e.g., as evidenced by publication in high-impact scientific journals), and demonstrated ability to conduct creative, independent research, are required.

Desired:

Experience in the following areas is highly desired: Gene editing technology (e.g., CRISPR); high-throughput screening methods; NGS; fluorescence and confocal microscopy; flow cytometry and FACS; mammalian and bacterial cell culture at Biosafety Level 2 or higher; and animal models of infectious disease.



Biotechnology and Bioengineering Department, located in Livermore, California and Emeryville, CA, performs biological and bioengineering research with applications in national security, healthcare and alternative energy. We are a diverse research group with a focus on both basic and applied biological research. We seek to address problems with strong ties to national security, such as biodefense and health security, through new research approaches and advanced technology development including microfluidics and nanofluidics. We also seek to develop the science base required by industry to produce clean, efficient, and cost-effective biofuels and other bioproducts on a commercial scale. This work is carried out in partnership with the Department of Energy's Joint BioEnergy Institute (JBEI). Our department is highly multidisciplinary, comprised of researchers with expertise in many disciplines of biology (molecular biology, microbiology, virology, immunology and biochemistry), chemistry (analytical, organic and physical) and engineering (chemical, mechanical and biomedical).


About Sandia:


Sandia National Laboratories is the nation?s premier science and engineering lab for national security and technology innovation, with teams of specialists focused on cutting-edge work in a broad array of areas. Some of the main reasons we love our jobs:

+ Challenging work withamazingimpact that contributes to security, peace, and freedom worldwide
+ Extraordinary co-workers
+ Some of the best tools, equipment, and research facilities in the world
+ Career advancement and enrichment opportunities
+ Flexible schedules, generous vacations,strongmedical and other benefits, competitive 401k, learning opportunities, relocation assistance and amenities aimed at creating a solid work/life balance*

_World-changing technologies. Life-changing careers._ Learn more about Sandia at: http://www.sandia.gov

*These benefits vary by job classification.



Security Clearance:


No clearance required.

This position does not currently require a Department of Energy (DOE)-granted security clearance.

Sandia will conduct a pre-employment background review that includes personal reference checks, law enforcement record checks, and employment and education verifications. Further, employees in New Mexico must pass a U.S. Air Force background screen for access to the work site. Substance abuse or illegal drug use, falsification of information, criminal activity, serious misconduct or other indicators of untrustworthiness can cause access to be denied or terminated, rendering the inability to perform the duties assigned and resulting in termination of employment.

If hired without a clearance, and one subsequently becomes required or you bid on positions that require a DOE-granted security clearance, a pre-processing background review that includes personal reference checks, law enforcement record and credit checks, and employment and education verifications may be conducted prior to a required federal background investigation. Applicants for DOE-granted security clearances must be U.S. citizens and be able to obtain and maintain the appropriate DOE security clearance as required for the position.

EEO Statement:

Equal opportunity employer/Disability/Vet/GLBT



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