The American Society of Mechanical Engineers (ASME)
1+ months

JBEI Postdoctoral Appointee - Biological Lignin Degradation

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We are seeking a postdoctoral associate to join our team working on understanding biological lignin degradation and conversion into valuable bioproducts\. The project team is working with scientists at the National Renewable Energy Laboratory to study enzymes involved in modification of lignin, include enzymes involved in depolymerizing lignin to smaller fragments and enzymes involved in metabolizing lignin derived compounds\. This work may also include studies of the structure of lignin modifying enzymes using X\-ray crystallography\. The postdoctoral researcher in this position is expected to have a strong background in molecular biology, biochemistry, enzymology and structural biology, particularly as they apply to studying lignin modifying enzymes\. The researcher will also collaborate closely with scientists at both SNL and at NREL, so the abilities to work in teams and communicate effectively are critical\.

On any given day, you may be called on to:

+ Expression of lignin modifying enzymes in bacterial and fungal expression systems;

+ Functional characterization of lignin modifying enzymes;

+ Develop robust analytical methods for monitoring lignin bond cleavage or modification\.

Depending on the candidate's background and interests work may also include:

+ Structural biology \(X\-ray crystallography, NMR\);

+ Computational biology and/or bioinformatics\.


+ PhD in Biochemistry, Molecular Biology, Biophysics, Chemistry or other relevant field;

+ Extensive experience in protein expression, purification, biophysical characterization and enzymology;

+ Demonstrated track record of publishing in peer\-reviewed scientific literature;


+ Strong interpersonal and communication skills;

+ Ability to work with multi\-disciplinary teams;

+ Previous research experience with lignin depolymerizing and modifying enzymes;

+ Previous research experience in the field of lignin depolymerization and development of assays methods for detecting lignolysis products;

+ Experience engineering enzymes for improved stability and performance;

+ Experience with high\-throughput enzyme assay development and enzyme mixture optimization;

+ Experience in X\-ray crystallography and/or NMR\.

Department Description:

The Biomass Science and Conversion Technology department is dedicated to developing and advancing innovative technologies for producing the next generation of biofuels\. Our multidisciplinary staff represents a diverse range of backgrounds and skill sets: molecular biology, chemistry, chemical and biochemical engineering, biophysics, computational science, and biochemistry\. We partner broadly with other Sandia departments as well as other national laboratories, industry, and universities to develop practical, science\-based solutions to national energy goals\. We also play an essential role in the DOE Joint BioEnergy Institute \(JBEI\), one of three Bioenergy Research Centers in the Nation advancing the next generation of biofuel technologies\.

About Sandia:

Sandia National Laboratories is the nations premier science and engineering lab for national security and technology innovation, with teams of specialists focused on cutting\-edge work in a broad array of areas\. Some of the main reasons we love our jobs:

+ Challenging work withamazingimpact that contributes to security, peace, and freedom worldwide

+ Extraordinary co\-workers

+ Some of the best tools, equipment, and research facilities in the world

+ Career advancement and enrichment opportunities

+ Flexible schedules, generous vacations,strongmedical and other benefits, competitive 401k, learning opportunities, relocation assistance and amenities aimed at creating a solid work/life balance\*

_World\-changing technologies\. Life\-changing careers\._ Learn more about Sandia at: http://www\.sandia\.gov

\*These benefits vary by job classification\.

Security Clearance:

This position does not currently require a Department of Energy \(DOE\)\-granted security clearance\.

Sandia will conduct a pre\-employment drug testing, and a pre\-employment background review that includes personal reference checks, law enforcement record checks, and employment and education verifications\. Further, employees in New Mexico must pass a U\.S\. Air Force background screen for access to the work site\. Substance abuse or illegal drug use, falsification of information, criminal activity, serious misconduct or other indicators of untrustworthiness can cause access to be denied or terminated, rendering the inability to perform the duties assigned and resulting in termination of employment\.

If hired without a clearance, and one subsequently becomes required or you bid on positions that require a DOE\-granted security clearance, a pre\-processing background review that includes personal reference checks, law enforcement record and credit checks, and employment and education verifications may be conducted prior to a required federal background investigation\. Applicants for DOE\-granted security clearances must be U\.S\. citizens and be able to obtain and maintain the appropriate DOE security clearance as required for the position\.

EEO Statement:

Equal opportunity employer/Disability/Vet/GLBT


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JBEI Postdoctoral Appointee - Biological Lignin Degradation

Sandia National Laboratories

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